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OPTIMASI FORMULA STICK BALM MINYAK ATSIRI DAUN SEREH (Cymbopogon citratus)

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ABSTRAK
Kandungan pada minyak atsiri daun sereh (Cymbopogon citratus) memiliki
efek sebagai neurobehavioral, sehingga minyak atsiri daun sereh dapat bermanfaat
sebagai aromaterapi. Untuk meningkatkan kenyamanan pengguna dan kemudahan
dalam pengaplikasiannya, diperlukan inovasi baru sediaan aromaterapi berupa
sediaan stick balm. Penelitian ini bertujuan untuk menentukan formula optimum
serta sifat fisik sediaan stick balm minyak atsiri daun sereh dengan variasi zat
tambahan cera alba dan lanolin. Minyak atsiri daun sereh diperoleh dengan distilasi
air dan dianalisis menggunakan GC-MS. Delapan rancangan formula stick balm
ditentukan menggunakan metode SLD (Simplex Lattice Design), dengan aplikasi
Design Expert 11, dan dibuat menggunakan metode peleburan. Stick balm diuji sifat
fisik meliputi uji pH, titik leleh, dan daya lekat. Respon uji sifat fisik diolah untuk
memperoleh formula optimum. Sediaan optimum stick balm diuji sifat fisik,
organoleptis, dan homogenitas. Hasil uji sifat fisik sediaan optimum diverifikasi
dengan metode one sample t-test menggunakan aplikasi SPSS. Nilai rendemen
minyak atsiri diperoleh sebesar 0,55%. Senyawa yang terkandung dalam minyak
atsiri daun sereh diantaranya diacetone alcohol, diethylacetaldehyde, beta-Pinene,
sulcatone, p-Cymene, dl-Limonene, dan 2,6-Dimethyl-1,6-octadiene. Hasil
optimasi formula diperoleh konsentrasi lanolin 5,310% dan cera alba 11,690.
Sediaan optimum stick balm berwarna kuning cerah, bau khas minyak sereh,
konsistensi semi padat, bahan tercampur homogen, nilai pH 5,63?0,06, titik leleh
44,5?0,5oC, dan daya lekat 2,437?0,106 detik, sehingga sediaan optimum stick
balm memenuhi syarat sifat fisik. Sifat fisik sediaan optimum tidak berbeda
signifikan dengan prediksi pada aplikasi Design Expert 11.
Kata kunci: optimasi, sereh, stick balm, simplex lattice design.viii
ABSTRACT
The content in lemongrass leaves essential oil (Cymbopogon citratus) has a
neurobehavioral effect, so lemongrass leaves essential oil can be useful as
aromatherapy. The stick balm form as an innovation of aromatherapy form is
required to increase the user?s comfort and ease of application of the product. The
aim of this study is to determine the optimum formula and physical properties of
lemongrass essential oil stick balm form with additive variations of cera alba and
lanolin. The lemongrass essential oil was obtained by water distillation and
analyzed by using GC-MS. Eight stick balm formula designs were determined by
using SLD (Simplex Lattice Design), method with Design Expert 11 software, and
made by using melting method. The stick balm forms were tested for the physical
properties such as pH test, melting point test, and adhesion test. The response to the
physical properties test was processed by using Design Expert 11 software to obtain
optimal formula. The optimal form of stick balm was tested for physical,
organoleptic, and homogeneity properties. The results of the physical properties test
of optimal formula were verified by using one sample t-test method with SPSS
software. The yield value obtained was 0,55%. The compounds contained in the
lemongrass essential oil include diacetone alcohol, diethylacetaldehyde, betaPinene, sulcatone, p-Cymene, dl-Limonene, and 2,6-Dimethyl-1,6-octadiene. The
results of the optimization of the formula were 5,310% of lanolin and 11,690% of
cera alba. The stick balm forms were bright yellow in color, have a characteristic
smell of lemongrass essential oil, semi-solid consistency, homogeneous mixed
materials, pH level of 5,63?0,06, melting point of 44,5?0,5oC, and adhesion tests
of 2,437?0,106 seconds, with the result that, the optimum formula of stick balm
met requirements for the physical properties. The physical properties of the optimal
formula are not significantly different from the predictions in the Design Expert 11
application.
Keywords: optimal, lemongrass, stick balm, simplex lattice design.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

141

Penerbit

Mataram : Farmasi FK Unram., 2021

Deskripsi Fisik

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Bahasa

Indonesia

ISBN/ISSN

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Klasifikasi

DTS 610 Iko o F.2021

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

SKRIPSI

Info Detail Spesifik

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Pernyataan Tanggungjawab

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Versi lain/terkait

Lampiran Berkas

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