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HUBUNGAN ANTARA KADAR KOLESTEROL HIGH DENSITY LIPOPROTEIN (HDL) SERUM DAN FRAMINGHAM STROKE RISK SCORE PADA PENDUDUK DI KECAMATAN SEKARBELA
ABSTRAK
HUBUNGAN ANTARA KADAR KOLESTEROL HIGH DENSITY LIPOPROTEIN (HDL) SERUM DAN FRAMINGHAM STROKE RISK SCORE PADA PENDUDUK DI KECAMATAN SEKARBELA
Rohmatul Hajiriah Nurhayati, Herpan Syafii Harahap, Mohammad Rizki
Latar Belakang: Stroke merupakan penyebab kecacatan dan kematian utama di dunia. Stroke iskemik merupakan subtipe stroke yang paling sering diderita. Pencegahan stroke iskemik dilakukan dengan menilai probabilitas terjadinya stroke iskemik seseorang dengan menggunakan Framingham stroke risk score. Faktor risiko lain untuk stroke iskemik yang perlu diperhatikan adalah penurunan kadar kolesterol HDL serum. Penelitian ini dilakukan untuk mengetahui hubungan antara kadar kolesterol HDL serum dan Framingham stroke risk score pada penduduk di Kecamatan Sekarbela Mataram.
Metode: Penelitian ini adalah penelitian deskriptif dengan rancangan cross sectional. Subjek pada penelitian terdiri dari 55 orang. Data karakteristik subjek yang ditunjukkan meliputi kadar kolesterol HDL serum dan berbagai faktor risiko dalam Framingham Stroke Risk Score disajikan dalam bentuk tabel.
Hasil: Penelitian ini diikuti 55 subjek dengan rerata usia 66,54 ± 7,816 tahun. Subjek dengan kadar kolesterol HDL serum rendah didapatkan sebesar 56,36% dengan proporsi tertinggi terdapat pada perempuan. Rerata tekanan darah sistolik subjek penelitian adalah 143,47 ± 25,54 mmHg. Proporsi subjek dengan penyakit diabetes melitus, penyakit kardiovaskular, hipertrofi ventrikel kiri, dan fibrilasi atrium tergolong rendah, sehingga rerata probabilitas risiko stroke iskemik yang didapatkan rendah yaitu 10,415%. Berdasarkan analisis Pearson didapatkan tidak adanya hubungan yang bermakna antara kadar kolesterol HDL serum dan Framingham stroke risk score (p>0,05).
Kesimpulan: Pada penelitian ini dapat disimpulkan bahwa kadar kolesterol HDL serum tidak berkorelasi dengan Framingham stroke risk score.
Kata kunci: Framingham stroke risk score, Kadar kolesterol HDL serum, stroke iskemik
ABSTRACT
RELATIONSHIP BETWEEN HIGH DENSITY LIPOPROTEIN CHOLESTEROL LEVEL WITH FRAMINGHAM STROKE RISK SCORE OF THE COMMUNITY OF SEKARBELA SUBDISTRICT MATARAM
Rohmatul Hajiriah Nurhayati, Herpan Syafii Harahap, Mohammad Rizki
Background: Stroke was a major medical problem that caused disablement and the most frequently causing death in the world. Ischemic stroke was the most common subtype of stroke. Prevention the occurrence of ischemic stroke can be initiated by assessing how much risk that one person may have using Framingham stroke risk score. Factors that could cause the stroke was the decreased of HDL cholesterol serum. This study was conducted to determine the relationship between high density lipoprotein cholesterol level with Framingham stroke risk score of the community of Sekarbela Subdistrict Mataram.
Methods: This study was a descriptive design with cross sectional design. The subject of this study consist of 55 subjects. The characteristics of subject include HDL cholesterol level and other risk factors in the Framingham Stroke Risk Score was served in tables. Results: This study followed 55 subjects with a mean age of 66.54 ± 7.816 years. Subjects with low HDL cholesterol serum obtained by 56.36% with the highest proportion are in women. The mean systolic blood pressure of the study subjects was 143.47 ± 25.54 mmHg. The proportion of subjects with diabetes mellitus, cardiovascular disease, left ventricular hypertrophy and atrial fibrillation is low. The results of this study was the community around Sekarbela Subdistrict had risk levels of stroke respectively 10,415% at low risk. Based on Pearson analysis, this study found no significant relationship between high density lipoprotein cholesterol level with Framingham stroke risk score (p>0,05).
Conclusion:There is no significant relationship between high density lipoprotein cholesterol level with Framingham stroke risk score.
Key words: Framingham stroke risk score, HDL cholesterol level, ischemic stroke
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